William Hill Brown's 'The Power of Sympathy or the Triumph of Nature Founded in Truth' was groundbreaking as it is recognized as the first American novel. Published in Boston, this novel, released in 1789, embodied the spirit of the American Enlightenment and mirrored the period's evolving social and cultural landscape. The novel's narrative revolves around themes of romantic love, moral dilemmas, and the consequences of actions, depicting the vulnerabilities of human emotions. As the plot unfolds, characters navigate their relationships against a backdrop of societal expectations and personal integrity.

Brown's work was not merely a story; it was also a vehicle for ideas and moral lessons that were pertinent during the late 18th century. The characters of the novel, such as the heartbroken protagonist, grapple with real emotional struggles, which made the book relatable to its readers. 'The Power of Sympathy' employs epistolary form, which utilizes letters as a primary means of storytelling. This stylistic choice was effective in conveying intimacy and emotional depth, thus engaging readers on a personal level.

The publication of this novel marked a significant shift in American literature, moving away from European influences and establishing a distinct American voice. It underscored the importance of individual experiences and emotional narratives, paving the way for future writers. Through this work, Brown contributed to the budding genre of American fiction, inspiring subsequent authors to explore similar themes, and it ultimately laid the foundation for a burgeoning literary tradition in the United States.