The marriage between King Henry VIII of England and Anne of Cleves was primarily a political maneuver rather than a romantic union. Following the rise of Protestantism in Europe, King Henry sought to strengthen his alliances with the Protestant states in the Holy Roman Empire. Anne of Cleves, a German noblewoman, was selected for her political connections and her ability to solidify trade routes and alliances, especially at a time when religious tensions were rising across Europe. The marriage ceremony took place at Hampton Court Palace, a symbol of Henry's power and status.

Initially, the marriage seemed advantageous. However, Henry was reportedly displeased with Anne upon their first meeting. He described her as unattractive, leading to significant discontent. This disillusionment resulted in the marital relationship deteriorating rapidly. Anne, for her part, was gracious and compliant, understanding the political nature of their union. Despite the challenges, she managed to hold herself with dignity throughout the brief marriage.

The marriage ultimately ended in an annulment just six months later, arranged amicably and without scandal. Henry, eager to marry again, soon took Anna Boleyn's cousin, Catherine Howard, as his next wife. Anne of Cleves, however, emerged from the annulment with a financial settlement and was even granted a place in the court, becoming known as the King's Beloved Sister.