Iran Aseman Airlines Flight 746 was a scheduled domestic flight from Isfahan to Tehran. On that fateful day, the Fokker 50 aircraft, a turboprop regional airliner, ascended from Isfahan International Airport. Shortly after takeoff, the flight reported encountering issues, including engine failure. The aircraft lost altitude rapidly and crashed near the town of Natanz, which is located in the Isfahan province of Iran. Eyewitnesses described a significant explosion upon impact, followed by a large plume of smoke visible for miles. Rescuers arrived at the scene, but sadly, all 66 passengers and crew members perished in the crash.

Investigations into the crash revealed potential mechanical issues, and the incident raised questions regarding Aseman Airlines' safety protocols and maintenance practices. In subsequent reviews, the Iranian aviation authority concluded that the flight may have encountered operational errors and equipment failures. This accident prompted discussions about aviation safety in Iran, particularly concerning aging fleets and the need for updated safety regulations. The wreckage of the aircraft was thoroughly examined, and the findings contributed to international aviation discussions on the importance of maintenance oversight in regional airlines.