The inauguration of the secondly-built Castellania in Valletta was a momentous occasion marked by the blessing of the newly constructed interior Chapel of Sorrows. The Castellania itself served as a symbolic center of both justice and governance in the city, reflecting the importance of administrative buildings in the 18th-century Maltese society under the Knights of St. John. The ceremony drew a large crowd from the local populace, eager to partake in this communal and spiritual event that underscored the role of the Church in public affairs.

The blessing ceremony was led by prominent local clergymen, who emphasized the connection between the administrative functions of the Castellania and the divine providence guiding the governance of the city. With religious rituals integral to the social fabric of 18th-century Malta, the ceremony not only marked the physical completion of the building but also reinforced the spiritual oversight thought necessary for justice and order. The Chapel of Sorrows, dedicated to the sorrows of the Virgin Mary, served as a place of reflection and moral guidance for those seeking justice.

The event was reflective of the era's values where civic duty intertwined with religious observance. The completion of the Castellania illustrated increasing investments in infrastructure that coincided with the growth of Valletta as a bustling urban center. Attendees experienced a blend of cultural, administrative, and religious life that characterized Malta’s capital, providing an opportunity for the citizens to celebrate their heritage and the advancements in their city’s governance and architecture.