Avioimpex Flight 110 was a domestic passenger flight operating in the region when disaster struck near Ohrid Airport. The Yakovlev Yak-42, a Soviet-made aircraft aircraft, was on approach after departing from Zurich, Switzerland, destined for Skopje. As the flight was completing its approach, it encountered severe weather conditions that led to a loss of control. Investigations suggested that poor visibility and possible pilot error contributed to the crash. All 116 passengers and crew aboard were killed, marking it as the deadliest aviation disaster in North Macedonia's history.

The incident provoked a thorough investigation into the factors that led to the crash. Focus was placed on the aging fleet of aircraft utilized by airlines in the region, further emphasizing the need for improved safety protocols. In the aftermath, the country's aviation authorities implemented stricter regulations regarding aircraft maintenance and pilot training to prevent such tragedies from occurring in the future. The crash became a pivotal point for discussions on air safety in the Balkan region, highlighting vulnerabilities in the aviation sector.

In addition to the direct impact on aviation policies, the crash also had a profound effect on the families of the victims and the society at large. The loss resonated deeply within the communities affected, fostering a culture of remembrance and a commitment to honoring those who perished. This event served as a stark reminder of the importance of aviation safety, particularly in the context of rapidly changing geopolitical environments.