The first edition of the Encyclopædia Britannica was published in Edinburgh, Scotland, under the editorial guidance of William Smellie. This ambitious project aimed to compile and present knowledge from various disciplines in a systematic and accessible format. Spanning three volumes, the work included contributions from a range of writers, and it was designed not only for scholars but also for the general public, reflecting the Enlightenment values of the time. This movement promoted reason, experience, and empirical evidence, marking a shift toward modern understanding and appreciation of science, philosophy, and culture.

The initial edition covered topics such as history, geography, and the sciences, paving the way for subsequent editions with more extensive entries. The Encyclopædia Britannica's publication was significant for its commitment to accuracy and thoroughness, distinguishing itself from other encyclopedic works of that period. It became a vital reference tool and a precursor to modern encyclopedias, influencing how knowledge was cataloged and shared in the ages that followed.

Furthermore, the publication played a critical role in the democratization of knowledge. By making information more accessible to an educated public, the Encyclopædia Britannica helped foster a culture of inquiry and critical thought, which would later fuel discussions about education reforms and accessibility during the course of the Enlightenment and beyond. Its lasting impact can still be felt today as it continues to adapt and expand its offerings in the digital age.