The Space Shuttle Columbia was launched on STS-35, marking one of NASA's pivotal missions in astrophysics. Onboard Columbia was the ASTRO-1 observatory, a unique spacelab designed to conduct astrophysical observations beyond the limitations of Earth's atmosphere. Ultraviolet observations, which are crucial for studying various celestial bodies, were made possible through ASTRO-1 due to the lack of atmospheric interference. This mission was launched from NASA's Kennedy Space Center in Florida, emphasizing the United States' investment in space science. The onboard instruments were designed to gather data on several significant astronomical targets, providing insights into the lifecycle of stars, the nature of quasars, and the characteristics of galaxies.The ASTRO-1 mission was notable not only for its scientific goals but also for its crew, which included a mix of experienced astronauts and specialists in scientific research. The mission duration was approximately 8 days, during which the crew operated the observatory, gathered data, and conducted experiments designed to advance the field of astrophysics. The data collected played a critical role in our understanding of phenomena such as gamma-ray bursts and stellar evolution. The successful execution of this mission paved the way for future astronomical missions and the development of more advanced space telescopes.