Airborne Express Flight 827, a Douglas DC-8 cargo aircraft, was on a scheduled flight from Louisville International Airport, Kentucky, to Roanoke Regional Airport, Virginia. On the fateful day, the flight was carrying out its routine operations; however, the weather conditions had deteriorated significantly as it approached its destination. The crew faced intense rain, fog, and mountainous terrain, which complicated their landing preparations. As the plane descended, communication with air traffic control took place, and the pilots reported difficulties due to the visibility issues caused by the inclement weather.

The aircraft eventually crashed in the vicinity of Narrows, Virginia, near the Appalachian Mountains. All six individuals on board, including the flight crew, tragically lost their lives. The National Transportation Safety Board (NTSB) subsequently conducted an investigation to determine the cause of the crash. They discovered that pilot decision-making under pressure and weather-related issues played significant roles in the accident.

This incident served as a critical reminder of the inherent risks involved in cargo aviation, especially under adverse weather conditions. Operators sought to improve weather training and operational protocols following the findings of the NTSB investigation, highlighting the importance of safety in the transport aviation sector.