The capture of the Castle of St. George marked a significant moment in the power dynamics of the Ionian Sea, as it was a key strategic location for both the Venetian Republic and the Spanish Crown. The collaboration between these two maritime powers was aimed at countering the increasing influence of the Ottoman Empire in the region. The successful joint military operation highlighted not only the military strength of the Venetian-Spanish coalition but also their commitment to maintaining their trade routes against external threats.

The operation commenced with meticulous planning, as the naval commanders coordinated their fleets to launch a surprise attack on the castle, which was held by local defenders. Their efforts proved fruitful, as the defenses were breached swiftly, allowing the joint forces to seize control of the fortress. The event not only demonstrated effective collaboration but also showcased the tactical superiority of the Venetian and Spanish forces.

By capturing the castle, Venice was able to reinforce its territorial claims in the Ionian Sea, enhancing its trade networks, while Spain benefitted from additional influence in maritime affairs. The successful operation served as an example of military cooperation in the face of common threats and paved the way for further joint endeavors in the region, reflecting the shifting alliances and hostilities characteristic of this period.