Great Ormond Street Hospital was founded in the mid-19th century in London, driven by a growing recognition of the need for specialized medical care for children. At the time, children's health needs were often overlooked by a healthcare system focused primarily on adults. The establishment of this facility marked a significant turning point in the availability of dedicated pediatric care, leading to improvements in the outcomes for young patients. The hospital began its journey with a small group of innovative leaders eager to create an institution that would focus solely on the treatment and well-being of children.

The hospital was among the first in the world to offer child-specific services, including surgeries, treatments, and inpatient accommodations designed to be friendly and accessible to young patients. Pioneers in medicine, such as Dr. Charles West, were instrumental in advocating for the importance of understanding children's unique physiological and emotional needs. Through research and compassionate care, the hospital set new standards in pediatric medicine, influencing hospitals worldwide.

Furthermore, Great Ormond Street became a hub for medical advancements and pediatric research over time. The hospital not only treated children but also trained medical professionals in the specialized care required for this vulnerable population. As such, it played an integral role in shaping the field of pediatrics, contributing to a growing understanding of children's health that has persisted into modern medical practice.