Ryan International Airlines Flight 590 was a scheduled flight operated by Ryan International Airlines, which tragically crashed shortly after takeoff from Cleveland Hopkins International Airport, Ohio. The incident occurred during a routine departure when the aircraft experienced mechanical failure and lost power shortly after liftoff. Investigations revealed that the aircraft had not been properly maintained, contributing to the unfortunate circumstances leading to the crash. The two pilots aboard were reported as the only individuals involved in the accident, and both were pronounced dead at the scene.

The aftermath of the crash prompted a comprehensive investigation by the National Transportation Safety Board (NTSB), which scrutinized the airline's operational protocols, maintenance records, and pilot training procedures. The investigation highlighted deficiencies in adherence to safety standards, raising important questions regarding oversight within the airline industry. The findings led to increased regulatory scrutiny and prompted improvements to safety regulations related to aircraft operation and maintenance practices. The crash ultimately served as a catalyst for change within the industry, emphasizing the critical importance of safety and adherence to maintenance protocols.

This incident also had implications for the public perception of regional airlines and influenced regulatory bodies to evaluate and amend policies that govern airline safety. Moreover, the event became a case study in aviation safety literature, often referenced in discussions about aviation regulations and the accountability of air carriers. As aviation technology and safety standards have evolved, this tragic event remains a reminder of the inherent risks of air travel and the continuous need for vigilance in ensuring passenger safety.