In February 1935, Caroline Mikkelsen made history by becoming the first woman to ever set foot on the Antarctic continent. This groundbreaking moment occurred during a Norwegian whaling expedition led by her husband, captain Klitgaarden Mikkelsen. The expedition aimed to explore the Southern Ocean and enhance whaling operations, which were economically significant at the time. Caroline Mikkelsen joined the crew, demonstrating her resolve and adventurous spirit, defying the conventional gender roles of her era. Her landing took place on an uninhabited island, known as Bouvet Island, which is located southeast of the mainland of South Africa. She stepped onto the ice, marking a crucial point in both Antarctic exploration and the broader narrative of women's participation in scientific and exploratory endeavors.

The event was not just a personal achievement for Caroline Mikkelsen but symbolized the expanding horizons for women during the early 20th century, who were actively seeking opportunities in fields traditionally dominated by men. Mikkelsen’s steps onto Antarctic soil echoed the challenges of overcoming societal expectations. Several years later, her expedition would resonate within the context of increased interest in polar science and the participation of women in various aspects of scientific research. Her contribution highlighted the potential for leadership and exploration beyond strict gender lines.

Caroline Mikkelsen’s landmark expedition contributed not only to the geographical knowledge of Antarctica but also provided inspiration for future generations of women in science and exploration. Her journey was one of courage and conviction, where she proved that the spirit of exploration belongs to everyone, regardless of gender. This event reshaped narratives around women’s capabilities and pushed boundaries in the pursuit of knowledge and adventure.