In March 2014, health officials in southeastern Guinea identified multiple cases of Ebola virus disease (EVD), marking a significant public health crisis. The outbreak was first reported in the forested rural regions, particularly focused around the village of Guéckédou. Investigations revealed that the first patient likely contracted the virus through contact with bats, a common carrier of the Ebola virus. Local health authorities, in conjunction with the World Health Organization (WHO), initiated immediate containment measures, including contact tracing and health education campaigns to inform the population about the disease, its transmission, and preventive measures. The initial spread was alarming, as the disease is known for its high fatality rates and potential for rapid transmission. The WHO declared the outbreak a Public Health Emergency of International Concern as the virus began to spread to urban centers and cross national borders into Liberia and Sierra Leone. As the crisis unfolded, the extent of the outbreak became unprecedented, involving thousands of confirmed cases across West Africa. Various international organizations, including Médecins Sans Frontières (Doctors Without Borders), mobilized to provide medical care, set up treatment centers, and support local healthcare systems overwhelmed by the surge of cases.As the epidemic continued, it was characterized by significant challenges faced by health workers, including cultural practices around burials that exacerbated the transmission of the virus. The need for international cooperation became apparent, with countries worldwide implementing travel restrictions and increased surveillance to prevent further spread. Despite the rising toll, the collective global response laid the groundwork for future public health strategies against Ebola and other infectious diseases.