The arrival of the first female prisoners at Auschwitz concentration camp in German-occupied Poland was a pivotal moment in the broader implementation of Nazi policies against perceived enemies, particularly Jews and political dissidents. These women, primarily members of the Polish resistance, were part of the Nazi regime's systematic effort to eradicate opposition and control occupied territories. The decision to house female prisoners indicated a shift in the camp's operational focus, as previously, Auschwitz mainly detained male inmates. The women endured severe conditions, marked by forced labor, starvation, and violence, as the camp was notorious for its inhumane treatment. This marked the beginning of a process that would contribute to the broader narrative of gender and the Holocaust.

As the months progressed, the number of female prisoners increased, and Auschwitz became a key site for the Nazi war effort in terms of forced labor. The operation faced challenges as the camp infrastructure had to be adapted to accommodate the unique needs of female inmates. Most women detained at Auschwitz experienced brutal treatment and were often separated from their families. While many would eventually be murdered, a few women managed to survive, which contributed to the post-war narratives and testimonies about the atrocities committed at Auschwitz. Holocaust survivors like Dr. Gisela G. were instrumental in documenting their experiences, providing invaluable firsthand accounts.