The Battle of Fardykambos took place in early March 1943, involving the Greek Resistance's armed confrontation with the Royal Italian Army. The Greek partisans, driven by the desire to liberate their occupied homeland from foreign control, engaged in guerilla tactics against an Italian battalion stationed near the town of Grevena. The Italian forces were met with unexpected resistance and superior local knowledge, which allowed the Greeks to exploit their strengths effectively. As the battle unfolded, the partisan forces initiated coordinated attacks, utilizing the terrain to their advantage.

The offensive lasted several days, from 3 March until the decisive victory was achieved on 6 March. By the end of the battle, not only had the Greek Resistance succeeded in forcing the surrender of the Italian battalion, but they also liberated Grevena from Axis control. This outcome was viewed as a significant morale boost for the Resistance and the local populace, marking a turning point in the struggle against occupation. It showcased the growing resolve of Greek partisans and their capability to challenge the occupying forces head-on.

The aftermath of the battle had broader implications for the Greek Resistance movement, as it encouraged further uprisings and instilled a sense of hope among the population. The victory demonstrated that organized resistance could yield tangible results against a structured military force, serving as a catalyst for more extensive engagements across Greece in the ensuing years.