The siege of Missolonghi began in 1825 during the Greek War of Independence, a pivotal conflict that sought to free Greece from centuries of Ottoman domination. The town, strategically located at a key point along the gulf, became a symbol of resistance as it withstood relentless assaults from Turkish troops. Throughout the year, the conditions within the town deteriorated severely due to constant bombardment, as well as extreme food shortages, which led to many inhabitants suffering from starvation or disease. The defenders included both soldiers and civilians, demonstrating a united front against the invaders.

By April 1826, the situation reached a critical point where the remaining residents, desperate for survival, decided to make a perilous exodus from their besieged home. The decision to leave was fraught with risk, as Turkish forces had encircled the town and were prepared to seize anyone trying to escape. Despite the imminent danger, the harsh realities within the walls compelled many to brave the escape, hoping to find refuge elsewhere.

The attempt to leave was both fraught with peril and imbued with desperation, as many were caught or killed during the escape. Only a small fraction of the inhabitants survived the treacherous journey, which illustrated the dire circumstances faced by those who resisted Ottoman authority. This event marked a critical point in the Greek struggle for independence and symbolized the extreme lengths to which people would go in their defense of liberty and homeland.