The final witchcraft trial in the United States began in Salem, Massachusetts, in 1878, ignited by the accusation from Lucretia Brown against Daniel Spofford. Brown, an adherent of Christian Science, alleged that Spofford had employed his mental powers to inflict harm upon her. This case drew significant attention as it invoked the historical context of Salem's notorious witch trials of the late 17th century, resonating within a society still grappling with the remnants of witchcraft hysteria. The trial captured public interest, reflecting a struggle between traditional beliefs and emerging modern ideologies around mental health and spirituality.

As the proceedings unfolded, the courtroom became a battleground for differing views on mental influence and the legitimacy of religious faith in the courtroom. The trial was less about physical evidence and more about the philosophical implications of mental power, showcasing the evolving landscape of legal definitions of harm. Experts were called to testify about the nature of mental injury and its implications, illustrating how religion and emerging psychological understandings were entangled within the trial's framework.

What made this trial notably different was its reliance on the doctrines of Christian Science, which emphasized the practices of prayer and spiritual healing over traditional medical approaches. Brown's claims highlighted a shift in societal views regarding spirituality and the mind's influence over physical health. Ultimately, the case concluded without a conviction, signaling the waning of witchcraft-related accusations in America and reflecting broader changes in societal beliefs about mental processes and religious practices.