Thado of Mohnyin's ascension to the throne marked a significant transition in the leadership of the Ava Kingdom in 1426. Following the death of King Mohnyin, Thado, a strategic governor from Mohnyin, wielded considerable influence and secured his position through alliances formed with key military and political figures. Under his leadership, Thado sought to unify the kingdom, which had been fragmented by internal rivalries and external invasions, particularly from neighboring states. His governance was characterized by efforts to strengthen the military and stabilize the economy of the kingdom, crucial for navigating the turbulent political landscape of the time.

Ava was known for its strategic location along lucrative trade routes, which offered both prosperity and vulnerability. Thado's ascension was not just a change of ruler but also reflected broader socio-political dynamics that influenced trade, culture, and military strategies in the region. He implemented policies aimed at fortifying cities and reinforcing the loyalty of vassal states to counteract any threats from rival factions.

Thado's reign also initiated cultural exchanges and advancements, fostering relationships with influential traders and neighboring territories. The capital city became a hub of culture and commerce, contributing to the economic stability of Ava and its prominence in Southeast Asia. His leadership style, combining military prowess with diplomatic negotiation, set the foundation for future rulers and impacted the historical trajectory of the Ava Kingdom toward greater territorial expansion.