Jacques Cartier, a French explorer, set sail for his second expedition to North America in 1535, determined to explore and establish relations in the New World. This journey was made more significant by Cartier’s use of three ships and a crew comprising 110 men, showcasing France's commitment to expanding its influence in the Americas. Among his passengers were the two sons of Chief Donnacona, a leader of the St. Lawrence Iroquois tribe, whom Cartier had captured during his first voyage. Their presence was intended to reinforce alliances and facilitate communication with indigenous groups.

Beginning his voyage from the port of Saint-Malo, Cartier navigated the Atlantic and reached the shores of Canada. He aimed to uncover valuable resources, particularly gold and spices, while also seeking a route to Asia. Cartier’s exploration of the St. Lawrence River was pivotal, marking the French claim to new territories. During this trip, Cartier not only charted significant geographic areas but also endeavored to learn more about the customs and languages of the native peoples, including the St. Lawrence Iroquois.

Throughout the journey, Cartier documented his encounters and observations meticulously, which would later inform and shape French colonial strategies in North America. His intentions were shaped by both a quest for wealth and a desire to spread Christianity among indigenous populations. Cartier's voyages laid the groundwork for future French settlements in the region, setting up initial connections that would be explored in subsequent colonization efforts.