Gerasim Izmailov was part of a series of Russian expeditions aimed at extending territorial claims and exploring new lands along the coasts of North America during the late 18th century. His journey toward Alaska was driven by the ambition of the Russian Empire to enhance its economic and political influence in the Pacific region, especially in the lucrative fur trade. Izmailov's voyage involved navigating treacherous waters and facing the challenges of the harsh climate typical of the North Pacific. The expedition was notable not only for its maritime difficulty but also for the various interactions it had with Indigenous populations, who were integral to the fur trade network. The success of the expedition provided valuable insights into the geography of Alaska, contributing to maps that would be used by subsequent explorers. Through his efforts, Izmailov contributed to the growing body of knowledge about the Arctic and subarctic regions, highlighting the burgeoning Russian interest in the New World during this period.

The experience of Izmailov and his crew provided detailed accounts of the natural resources and landscapes they encountered, enriched by direct observations of local Indigenous cultures. His reports indicated potential for trade and resource extraction, which captured the interest of Russian merchants and the crown. In the years following his arrival, the Russian American Company engaged more vigorously in commerce and settlement activities in the area, dramatically changing the social and economic landscape. Izmailov's expedition thus served as a precursor for future Russian explorations in North America, paving the way for the establishment of Russian settlements and forts along the Alaskan coast.