The publication of Charilaos Trikoupis's manifesto, "Who's to Blame?," in the Athens daily Kairoi marked a pivotal moment in the political landscape of Greece. Trikoupis, a political figure emerging from the late 19th-century upheaval, was concerned with the political and social direction of Greece under King George I. In his manifesto, he outlined his grievances against the monarchy, which he believed held excessive power and was negatively impacting governance and democratic processes. This manifesto captured the discontent of a populace longing for reform and accountability in their leaders.

Trikoupis's manifesto resonated deeply with the citizens of Greece, as it boldly addressed issues that many felt were overlooked by the ruling monarchy. The piece not only called into question the role of King George but also advocated for a more participatory form of government, reflecting the growing desire for a political system that truly represented the will of the people. The manifesto's publication sparked widespread discussions in political circles and among ordinary citizens, leading to an enduring legacy of political activism.

The subsequent election of Charilaos Trikoupis as Prime Minister the following year served as a testament to the manifesto's influence and the shifting tides of Greek politics. His election marked a significant change in leadership, indicating a move towards a more progressive and reform-minded government. As Prime Minister, Trikoupis aimed to implement policies that addressed the concerns he had articulated in his manifesto, thereby elevating the importance of public discourse in Greek politics and establishing his role as a key figure in the pursuit of democratic reform.