Simon de Colines, a significant figure in Renaissance printing, published a critical commentary on the Gospels titled 'Commentarii initiatorii in quatuor Evangelia', authored by Jacques Lefèvre d'Étaples, an influential theologian and pioneer of biblical humanism. Lefèvre's work was among the first to encourage a closer reading of biblical texts, emphasizing the original meanings, which diverged from traditional interpretations upheld by the church. This commentary aimed to make Biblical teachings more accessible, thereby contributing to the reformist discourse of the time.

However, the Parisian Faculty of Theology, guardian of doctrinal purity and academic scrutiny, viewed Lefèvre's work as potentially heretical. The faculty imposed a fine on Simon de Colines for disseminating ideas they deemed inappropriate, mirroring the broader struggles between scholarly inquiry and ecclesiastical authority. The critique of Lefèvre's interpretation by the Faculty represents a critical juncture in the history of biblical scholarship, where emerging humanist thought clashed with the rigid dogmas of medieval theology.

Furthermore, this conflict was emblematic of the wider Reformation movements sweeping through Europe, challenging established norms and paving the way for new theological paradigms. The event poignantly illustrates the perilous landscape for printers and authors advocating for intellectual freedom and reform amidst an era of intense scrutiny and censorship within ecclesiastical institutions. It also showcased the growing pressure upon theologians and scholars who endeavored to foster a more accessible understanding of scripture, risking their livelihoods and reputations in the process.