The marriage between Willem of Orange and Anna of Saxony represented a crucial alliance during a period of intense political upheaval in Europe. Willem, recognized as a central figure in the revolt against Spanish rule in the Netherlands, sought to establish powerful connections that would aid his cause. Anna, being a member of the influential saxon ducal family, was a key ally in this pursuit. The wedding took place in Dresden, the capital of Saxony, reflecting the political importance of the union. The ceremony was attended by influential nobles and symbolized the ongoing trend of dynastic marriages aimed at consolidating power and influence across regions.

The union was not only significant in the context of the personal lives of those involved but also had broader socio-political implications. At that time, the Netherlands was embroiled in conflict with Spain, and Willem's marriage to Anna was perceived as a strategic move to garner support from Protestant factions. The Saxony family's influence could bolster his resistance against the Catholic Habsburgs, who sought to retain control over their territories in the face of rising Protestantism. Furthermore, the marriage underscored the role of women in these political strategies, as marriages were often tools for alliance-building.

In the years following their wedding, Willem of Orange continued to lead the Dutch revolt, consistently seeking to solidify alliances through marital ties. The couple had several children, further intertwining the Orange lineage with the Saxon nobility. Their offspring continued to play significant roles in European politics, demonstrating the long-lasting effects of such alliances. The marriage thus not only marked a personal union but also a pivotal moment in the history of the Dutch struggle for independence, setting the stage for future conflicts and political maneuvers.