Pope John XXII took a pivotal step in establishing the roots of Christianity in India by erecting the first diocese in Quilon. This move, aimed at enhancing the ecclesiastical structure of the church in Asia, was propelled by the need for organized governance over Christian communities in a vast and culturally diverse land. The appointment of Jordanus, a French-born cleric, to the position of the first Bishop of Quilon illustrates the international aspect of the Church’s mission during this period. It was more than just an administrative decision; it represented a critical juncture in the history of Christianity in India, intertwining local practices with European ecclesiastical traditions.

Jordanus' leadership was significant as he was tasked with overseeing the spiritual welfare of Christians as well as engaging with the local communities and their cultures. The presence of a diocese established a formal religious authority that would aid in catechism and the establishment of churches. This event was indicative of the missionary zeal of the Church presiding over global expansion during the 14th century, reflecting the dynamics of cultural exchange.

The formation of the diocese also facilitated trade relations and intercultural connections, as Quilon was a major trading hub. The church’s establishment in such a vital location helped deepen the ties between Christianity and local customs, leading to a unique synthesis which would shape the trajectory of Christianity in India going forward. The Church's role in education and community service developed through the diocese would echo throughout Indian history, laying foundational stones for future interactions between European and Indian societies.