The Macedo-Romanian Cultural Society emerged during a period of profound change for both Romania and the ethnic Romanians living in Macedonia, who faced significant cultural and political challenges under the Ottoman Empire. The society was established to serve as a platform for the preservation and promotion of Romanian culture, language, and heritage in a region where it was at risk of being marginalized. The founders recognized the need for organized efforts to protect their cultural identity, amidst the increasing pressures of nationalism and imperialism in the Balkans. Bucharest, as the capital city, served as a pivotal location for this movement, being both the heart of Romanian culture and politics.

The society would organize events, publish materials, and serve as a vocal advocate for the rights of Romanians in the region. Through these initiatives, the Macedo-Romanian Cultural Society aimed not only to bolster local community morale but also to gain the attention of Romanian politicians and the broader European audience regarding their plight. The club included prominent intellectuals, writers, and politicians dedicated to fostering a cohesive Romanian identity amongst scattered communities in Macedonia, where Turkish dominance was prevalent.

One notable aspect of the society's formation was its connection to the wider movements of the time that sought to unify and empower national identities across Europe. The society’s activities linked cultural pride with political activism, promoting the idea that political rights should accompany cultural recognition, thus setting a precedent for future nationalist movements in the Balkans. By focusing on education and literature, the Macedo-Romanian Cultural Society would contribute significantly to the Romanian cultural renaissance that marked the late 19th and early 20th centuries.