The Treaty of Selymbria was a pivotal agreement concluded in 1411 that sought to resolve the ongoing conflicts between the Ottoman Empire and the Republic of Venice concerning trade dominance and territorial rights in the Eastern Mediterranean. Both parties had engaged in a series of military confrontations, primarily centered around the strategic control of trade routes vital for commerce in the region. The negotiations took place in Selymbria, a significant location on the European side of the Sea of Marmara, underscoring its importance as a trade hub. Both empires recognized their mutual dependencies, leading to the conclusion of a treaty intended to stabilize their relationship.

The terms of the treaty included concessions from both sides, which facilitated commercial access and delineated specific territorial boundaries. It arose in a context where both states were seeking to bolster their influence and economic vitality against the backdrop of other regional powers. The conclusion of the treaty was facilitated by experienced diplomats from both empires, signaling a willingness to engage in diplomacy rather than prolonged warfare. The treaty not only emphasized trade, which was essential to both empires' economies but also symbolized a recognition of the necessity of coexistence in a competitive geopolitical landscape.

Further, the Treaty of Selymbria had lasting implications for future Ottoman-Venetian relations, allowing for enhanced trade and diplomatic ties which would develop over the subsequent decades. Otoman expansion was somewhat curtailed, while Venice preserved its commercial interests. This agreement set a precedent for future negotiations between both parties, influencing their interactions during a critical period of change in Eastern Mediterranean politics, where emerging empires were vying for supremacy. The successful negotiation displayed the complexities of diplomacy in the face of military might, showcasing a mature approach to international relations in the context of the time.